INCIDENCE STUDY OF ROTAVIRUS ANTIGEN IN DIARRHEIC STOOL OF CHILDREN ATTENDING SABANA SPECIALIST HOSPITAL IN GOMBE, NIGERIA

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  • Department: Microbiology
  • Project ID: MCB0212
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ABSTRACT


 Rotavirus is a common cause of diarrhea in children. This study was carried out to determine the prevalence of rotavirus antigen in children below five years presenting with diarrhea in Gombe State. Thirty (30) stool samples were analysed using ELISA KIT. Out of the total number of samples analyzed, a prevalence of 6.67% was recorded all of which are between the age group 7-12 months. A more comprehensive survey is recommended to depict true states of rotavirus as an etiology of diarrhea in the study area.


Chapter One


1.0 Introduction:…………………………………………………………..1


1.1 Statement of problem:……………………………………………….2


1.2 Justification:……………………………………………………………3


1.3 Aims and objectives…………………………………………………..3


1.4 Scope / limitation:……………………………………………………4


Chapter Two


2.0 Literature review:……………………………………………………..5


2.1 Discovery of rotavirus:………………………………………………7


2.2 Importance of rotavirus infection…………………………………8


2.3 The rotavirus genome:………………………………………………9


2.4 Clinical symptoms of rotavirus infections:…………………….11


2.5 Transmission of rotavirus infections:…………………………..13


2.6 Pathophysiology of rotavirus diarrhea:…………………………14


2.7 The current model of diarrhea induction by rotavirus………18


2.8 The molecular basis of diarrhea induction………………….…20


2.9 Systemic infection with rotavirus:……………………………….26


Chapter Three


3.0 Methodology………………….………………………………………34


3.1 Study Site……………………………………………………………..34


3.2 Inclusion and Exclusion Criteria.………………………………..35


3.3 Sample Collection..………………………………………………….35 


3.4 Methods……………………………………………………………….35


3.4.1 Procedure…………………………………………………………...35


Chapter Four


4.0 Result…………………………………………………………………..37


4.1 Table 4.1……………………………………………………………….38


4.2 Table 4.2……………………………………………………………….39


Chapter Five


5.0 Discursion……………………………………………………………..40


5.1 Conclusion…………………………………………………………….41


5.2 Recommendation…………………………………………………….41


References…………………………………………………………………43


 


 


INCIDENCE STUDY OF ROTAVIRUS ANTIGEN IN DIARRHEIC STOOL OF CHILDREN ATTENDING SABANA SPECIALIST HOSPITAL IN GOMBE, NIGERIA
For more Info, call us on
+234 8130 686 500
or
+234 8093 423 853

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  • Type: Project
  • Department: Microbiology
  • Project ID: MCB0212
  • Access Fee: ₦5,000 ($14)
  • Pages: 3 Pages
  • Format: Microsoft Word
  • Views: 720

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