TABLE OF CONTENTS
DECLARATION ................................................................................................................ ii
APPROVAL...................................................................................................................... iii
DEDICATION................................................................................................................... iv
ACKNOWLEDGEMENT....................................................................................................v
LIST OF TABLES AND FIGURES................................................................................... ix
ABBREVIATIONS .............................................................................................................x
ABSTRACT ........................................................................................................................1
CHAPTER ONE..................................................................................................................2
1.0 Introduction.............................................................................................................2
1.2 Problem statement..........................................................................................................4
1.3. Objectives of the study ................................................................................................4
1.3.1. General objectives...............................................................................................4
1.4 Justification of the study..........................................................................................5
1.5 Significance of the study .........................................................................................5
1.6 Scope of the study ...................................................................................................5
1.6.1 Time scope...........................................................................................................5
1.6.2 Content scope.......................................................................................................5
1.6.3 Geographical scope ..............................................................................................5
1.7 Conceptual frame work ..................................................................................................6
CHAPTER TWO .................................................................................................................7
LITERATURE REVIEW.....................................................................................................7
2.0 Introduction.............................................................................................................7
2.1 General prevalence of schistosomiasis............................................................................7
2.2 Factors associated with occurrence of schistosomiasis in Uganda ............................8
2.2.1 Socio-demographic factors...................................................................................8
2.2.2 Age (person).........................................................................................................8
2.3.3 The environment ..................................................................................................8
2.3.4 Immigration..........................................................................................................8
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2.3.5 Socio-economic factors ........................................................................................9
2.3 Clinical presentations of Schistomiasis....................................................................9
CHAPTER THRE..............................................................................................................11
METHODOLOGY ............................................................................................................11
3.1 Study area .............................................................................................................11
3.2 Study design..........................................................................................................11
3.3 Sample size determination.....................................................................................11
3.4 Study population ...................................................................................................11
3.5 The sampling method ............................................................................................11
3.6 Inclusion and exclusion criteria .............................................................................11
3.6.1 Exclusion criteria................................................................................................11
3.7 Data collection method..........................................................................................12
3.7.1 Semi-structured questionnaire ............................................................................12
3.8 Research instruments.............................................................................................12
3.8.1 The reagent strip.................................................................................................12
3.9 Data analysis method.............................................................................................12
3.10 Study limitations .................................................................................................13
3.11 Data quality control.............................................................................................13
3.12 Ethical consideration ...........................................................................................13
CHAPTER FOUR..............................................................................................................14
RESULTS..........................................................................................................................14
4.1 Socio-demographic characteristics of the study population ....................................14
4.2 Prevalence of schistosomiasis among the participants…………………………….15
4.3 Distribution of schistosomiasis among the socio-demographic characteristics .......16
4.4 Factors associated with prevalence of schistosomiasis among patients...................18
4.5 Risk factors associated with prevalence of schistosomiasis among participants......20
4.6 Assessment of participants’ knowledge about schistisomiasis................................22
CHAPTER FIVE: ..............................................................................................................25
DISCUSSION....................................................................................................................25
5.1 Discussion of results..............................................................................................25
5.2 Conclusions..................................................................................................................28
ABSTRACT
Introduction: Schistosomiasis is one of the most serious prevalent diseases worldwide and it remains a life-threatening public health problem in many developing countries particularly in rural communities. The study was aimed at determining the prevalence of schistisomiasis among patients attending General Out Patient Department (GOPD) Kilembe Mines Hospital in Kasese district. Methods: A retrospective-cross sectional descriptive study was carried out where, semi structured questionnaires were used to generate data on expose risk factors. The data was analyzed using SPSS-version 20 to generate frequency, median and proportions. Binary logistic regression model was used to perform both bivariate and multivariate analysis to obtain crude and adjusted odds ratios for the associated factors of schistosomiasis. Statistical significance was considered at p-value ≤0.05. Results: The prevalence of 5(2.5%) schistosomiasis infection was obtained out of 200 patients studied at the hospital. The participants who didn’t boil water for drinking were 1.13 times more likely to be infected 4(2.5%) compared to those who boiled drinking water1(2.4%), this was statistically significant (OR=1.13, 95% CI; 1.079-6.120). The males participants were more infected 3(3.3%) compared to female. Additionally, those who lacked latrines at home were also at a higher risk of being infected 3(3.1%) as compared to those who had, although these factors were not statistically significant. Conclusions: Drinking unboiled water was a major significant risk factor for occurrence of schistisomiasis among the studied participants. There is need for continuous health education, sensitization about schistisomiasis and periodic school-based and community based drug distribution. This will help to reduce the prevalence and morbidity of schistosomiasis among these communities.