color:windowtext">ABSTRACT
The
place of adequate nutrition in the live of the young especially in the recently
weaned cannot be overemphasized. The abrupt change in diet, leading to possible
immune system weakness and disease conditions, is a focal point in the care of
the young. This project examined serum globulin and bilirubin levels in
weanling rats whose feed was supplemented with Emilia sonchifolia leaf extract. The extract was also screened for
phytochemical contents and the effect of its supplementation in liver enzymes (AST,
ALT and ALP) activities.
TABLE OF CONTENTS
Title page
Abstract
Dedication
Acknowledgement
Certification
Table of Contents
List of Tables
color:windowtext">CHAPTER ONE: INTRODUCTION
1.1 Background
of the study 1
1.2 Statement
of the problem 7
13 Aim
and Objectives of the Study 8
1.4 Research
questions 9
1.5 Significance
of the study 10
1.6 Scope
of the study 10
color:windowtext">CHAPTER TWO: LITERATURE
REVIEW
2.1 Emilia sonchifolia: History and Ethnobotanical
applications 11
2.2 Botanical
description 14
2.3 Proximate
Composition of Emilia sonchifolia leaf 17
2.4 Anti-nutritional
Factors 18
2.5 Effect
of oral administration of Emilia sonchifolia leaf
in Wistar rats 19
2.6 Serum
globulin and its clinical relevance 21
2.7 Serum
bilirubin and its biochemical effects in animal 23
2.8 Kidney
function parameters and its relevance in health
and disease 25
color:windowtext">CHAPTER THREE: MATERIALS
AND METHODS
3.1 Materials 27
3.2 Site
of Study 27
3.3 Plant
collection and extract preparation 27
3.4 Experimental
animals 28
3.5 Experimental
diet 29
3.6 Metabolic
studies 29
3.7 Methods 29
3.7.1 Estimation of serum globulin using (manufacturer protocol) 29
3.7.2 Estimation of serum bilirubin level 30
3.8 Quercetin
standard drug (administered as a single dose
in
one group of experimental animals) 30
3.9 Economic
Analysis/Limitation 31
3.10 Statistical Analysis 31
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color:windowtext">CHAPTER FOUR: RESULT
AND DISCUSSION
4.1 Results
4.2 Discussion
color:windowtext">CHAPTER FIVE: SUMMARY
AND CONCLUSION
5.1 Summary
5.2 Conclusion
5.3 Recommendations
References